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A new test to identify abnormal wear and loosening of titanium implants

Identifies abnormal wear of titanium arthroplasty components with a high degree of accuracy
94%

Sensitive

96%

Specific

How does it work?

Fric[Ti]onTM uses a simple blood sample that is then sent to our partner lab for testing using inductively coupled plasma mass spectrometry. Following analysis, results are emailed directly to the requesting surgeon.
Lady having blood drawn from her arm
Worn tibial tray

How was the test developed?

At ExplantLab, we have investigated the relationship between implant wear, blood metal ion concentrations and patient outcomes for nearly twenty years.

Using our implant retrieval unit, we have been able to examine explanted prostheses to correlate direct physical findings with blood metal ion and tissue results.

Our research challenges the idea that “loosening” is a binary concept.  Before a component becomes fully detached, micromotion gradually increases over time.

As micromotion increases, the component wears against the surrounding cement or bone, shedding metal debris. This debris can be measured in blood samples.

Through the comparison of patients who have had excellent outcomes with those who have undergone revision surgery, we have been able to establish titanium concentrations which reliably identify abnormal wear of titanium components.

Benefits of Fric[Ti]onTM
Waiting times for CT and bone scans scans, and delays in reporting are a challenge in many trusts (Royal College of Radiology).  
Fric[Ti]onTM can provide insights in to implant performance before scans are even scheduled and can avoid patients’ exposure to radiation.
Pricing

Test kits are £125 each and can be ordered in multiples of 5 or 10 kits.

Discounts are available for higher volume orders.

Email friction@explantlab.com to order test kits or complete the contact form.

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Q&A

Q - I already have access to a lab that tests titanium ion concentrations, can I use my lab?
A – ICPMS titanium testing is very sensitive and results vary from lab to lab. ExplantLab has partnered with a specific lab and clinically validated their ICPMS apparatus to support Fric[Ti]on testing.

Q – I’d like to place a bulk order. What discount is available?
A – Please contact us at friction@explantlab.com and we can discuss your needs.

Q – Can I order Fric[Ti]on through the Trust pathology lab?
A – We can work with your pathology lab to get this on the trust system. This can take time, and in the meantime, ordering kits directly is the quickest way to access testing for your patients.